Kunzima kumuntu ovamile ukuthi acabange ukuthi umama ozayo uzozizwa kanjani uma imiphumela ye-ultrasound noma i-biochemical screening testing in the baby ibonise ingozi yokukhubazeka ngokwezakhi zofuzo. Futhi nakuba ku-1 kuphela kwezingu-10 ukuhlolwa okunjalo kuqinisekiswa ukuhlolwa okuningiliziwe, kuyisidingo sokuxilongwa kabusha okwesabisa abesifazane abakhulelwe kakhulu.
Iphuzu lukuthi ukuphikisa noma ukuqinisekisa ukuxilongwa okubi, kubalulekile ukuhlaziya i-karyotype ye-fetal, lapho iningi lemitholampilo isebenzisa izindlela ezingavamile zokuhlunga isampula sampula-sithandwa yocwaningo, i-amniocentesis (i-fetal amniocentesis) nesampula legazi lezintambo (cordocentesis). Ngaphezu kokukhathazeka kwenqubo ngokwalo, kungaba nemiphumela emibi kunazo zonke, phakathi kokuphazamiseka kokukhulelwa. Lesi sici sibangela abanye besifazane ukuba bayeke ukuxilongwa okunjalo futhi ngaleyo ndlela baziveze esimweni esicindezelayo phakathi nesikhathi sokukhulelwa, okungenakuthinta ngisho nengane ephilile ngokuphelele.
Kungani ukuhlaziywa kwe-fetus karyotype?
Lapho isifo sesifo sokubeletha ngaphambi kokubeletha ngemuva kwesonto le-11 lokukhulelwa, i-ultrasound inqunywe. Kanye nama-ultrasound, izimpawu ze-biochemical ziyacutshungulwa. Inhloso yalezi zinqubo ukuchaza lokho okuthiwa yiqembu eliyingozi. Kodwa-ke, ukuxilongwa okunjalo kungabonisa kuphela amaphesenti amancane amathuba okuthola izakhi zofuzo futhi akunakwenzeka ukufaka ukuxilongwa okuqinisekisiwe kwimiphumela yayo. Ngosizo lokuhlaziywa okuningiliziwe kwe-karyotype ye-fetus, kungenzeka ukunquma ngezinga eliphakeme lemathuba okungafani okulandelayo, okwenza ukwelashwa kuthiwa yi-syndromes:
- Phansi;
- Edwards;
- I-Patau;
- U-Shereshevsky-Turner;
- Klinefelter.
Indlela engavamile yokuxilongwa nge-pathologies ye-chromosomal
Ekupheleni kwekhulu leminyaka elidlule, i-DNA ye-fetal itholakala egazini lomfazi okhulelwe. Kodwa-ke, eminyakeni engama-20 kuphela kamuva, ngokuthuthukiswa kwe-nanotechnology, ukuhlolwa kwe-DNA ngaphambi kokubeletha kwakungasetshenzisiwe kusetshenziselwa ukwelashwa okusebenzayo. Okuyinhloko yale ndlela kuhlanganisa ukuhlukanisa i-DNA eyengeziwe ye-fetus nomama kusuka egazini elibi lomama bese lixilonga ukuba khona kwezinto ezingavamile ze-chromosomal. Lolu cwaningo lubizwa ngokuthi ukuxilongwa kwe-trisomy enkulu noma ukuhlolwa kwe-DOT.
Inzuzo enkulu yokuhlolwa kwe-DOT ukuphepha ngokuphelele kowesifazane kanye nengane yakhe. Ngaphezu kwalokho, kungenziwa nganoma yisiphi isikhathi ngemuva kweviki le-10 lokukhulelwa, futhi imiphumela izobe ilungile ezinsukwini ezingu-12 kusukela ku-99.7% ukuzethemba. Ukuxilongwa okunjalo kuboniswa ikakhulukazi kwabesifazane abasengozini yokuthola isifo sokuqala sokubeletha ngaphambi kokubeletha. Ama laboratories ambalwa kuphela e-China, e-US naseRussia asebenzisa le ndlela ngemithi yokwelapha. Ezweni lakithi, ukuhlolwa kwe-DOT kungenziwa kuphela ebhokisatriji "ye-Genoanalyst", ochwepheshe bayo abathuthukisi bezobuchwepheshe. Ukuze kuqaphele ukutholakala kokuhlaziywa okunjalo kwabesifazane kunoma yikuphi indawo eRussia, ukuqoqwa kwegazi kungenziwa esikhungweni sezokwelapha esiseduze, emva kwalokho okushiwo yi-biomaterial kuhanjiswa eMoscow ngenhloso yokuhlolwa kwe-DOT usebenzisa isevisi ekhethekile yeposi. Nakekela impilo yengane yakho ngaphambi kokuba azalwe. Impilo kuwe kanye nezingane zakho ezizayo!