Ukungafani okuqukethwe amaphesenti wokugcina - yilokho okwenza umuntu ngamunye ayingqayizivele. Kwezinye izimo, ukuhlola izici ezizuzwe njengefa zabazali nezinye izihlobo kungabikezela ukuthi yiluphi uhlobo lesi sifo esiyoba khona. Kucatshangwa ukuthi ingane iyobafana kakhulu nabazali bayo, okungukuthi, banokuphakama okufanayo kanye nomzimba futhi, ezimweni eziningi, umbala ofanayo wezinwele nokubukeka. Kunezici eziningi izingane ezingathola ifa kubazali bakhe, kubandakanya amathalenta noma amakhono ezindaweni ezahlukene kanye nezimfanelo zomzimba. Kumuntu, ingozi ye-gout iphindwe izikhathi ezingu-8 kunabesifazane abangaphambi kokuya esikhathini abavame ukubhekana nalesi sifo. Isikhathi esivame kakhulu sokuhlaselwa kokuqala sivela eminyakeni engu-30 kuya kwengu-60. Ezinye izici zengozi:
• Ukusebenzisa kakhulu utshwala. Ngokwalo, utshwala abubangeli igciwane, kodwa kubangela ukucindezela kweziguli.
• Ukudla okuphezulu kwamaprotheni.
• Umjaho - isibonelo, eMaori nasePolynesia, izinga le-uric acid egazini ekuqaleni liphakeme kunelobanye abantu, ngakho-ke bajwayele ukuvuza.
• Ukukhuluphala.
• Izifo ezenza izinga eliphezulu lokuvuselelwa kwamaseli, njenge-erythremia (ukukhushulwa kwe-erythrocyte), kanye nama-lymphomas kanye nezinye umdlavuza.
• Ukuba khona kwe-gout kumlando womndeni.
• Ukuthatha ama-diuretics noma amancane amanani okuphuma kwe-salicylic acid.
• Isifo sezinso.
Abantu ababhekene ne-gout banomngcipheko okhulayo wokuthuthukisa ukukhathazeka kwe-lipid metabolism nomfutho wegazi ophezulu. Ku-25% weziguli, ngisho nangaphambi kokuhlaselwa kokuqala kwe-gout, kunezimo ze-renal coal ezihlobene nokufakwa kwama-crystals e-uric acid ezinso. Ngokuhlaselwa okunamandla kwe-gout ye-in vitro articular deposition, izidakamizwa ezingekho-steroidal ezilwa nokuvuvukala (i-NSAID) ziphumelela kakhulu. Kufanele banikezwe ngamazinga aphezulu emazingeni okuqala okuhlaselwa; Abaningi abagulayo abagulayo bayazigcina zikhona. Kulabo abangakwazi ukuthatha ama-NSAID, omunye wemithi eyaziwayo endala - i-colchicine ihlala.
Ukungalungi
Izinkinga eziyinhloko ze-colchicine yindlela elula kakhulu yokwelashwa kanye nengozi ephezulu yemiphumela emibi. Ama-NSAID esekelwe kuma-salicylic acid derivatives ngamanani amancane akhulisa i-gout, kanti nakuba ngokulinganiselwa okukhulu kusebenza kahle ngokumelene nalesi sifo, kusobala ukuthi ukusetshenziswa kwawo kusengcono kakhulu kugwenywe. Ngokudabukisayo, ukusetshenziswa okuyisisekelo kwe-allopurinol, isidakamizwa esasetshenziswa kakhulu ukuvimbela ukugubha ne-gout, kungase kube khona ukuhlasela kwe-articular. Ukuxilongwa kwe-gout kwenziwa ngesisekelo sezimpawu zomtholampilo, ukutholakala emlandweni wesiguli wezinto ezibalulekile kanye nokuhlolwa kwegazi okuqukethwe kwe-uric acid. Uma kukhona ukungabaza, ukuxilongwa kungaqinisekiswa ngokutholakala kwamakhekhedi e-sodium urate kwisampuli se-synovial fluid. Ku-gout okungavamile, amalunga angabhubhisa, futhi ukuhlola kwe-X kuzobonisa izinguquko ezijwayelekile. Ukwengeza, ukuvuthwa kufakwa ezinhlobonhlobo ngendlela yama-nodules amancane ahlonishwa kalula azungeze amalunga, izikhwama ze-articular, amagobolondo we-tendon nama-shell eartilaginous ear shells.
Ukuxilongwa okuhlukile
Ukuhlasela okunamandla kungahlala emahoreni amaningana kuya emavikini amaningana. I-gout enhle ivame ukufana ne-arthritis ehlanzekile, futhi ukufakwa esibhedlela kungadingeka ukuba kungabikho lesi sifo esibi kakhulu. Ngokufanayo, i-arthropathy yokuvuvukala ingaqala nge-monoarthritis efana ne-gout. Ukwandisa izinga le-uric acid ngokwakho akufanele kube yisisekelo sokwelashwa kwezidakamizwa. Iningi leziguli ezinamazinga e-uric acid ephakeme kulo lonke impilo yazo ngeke zithole izimpawu ze-gout. Abanye babo kuphela abazobhekana nokuhlukunyezwa okuphindaphindiwe. Kodwa ngisho nakulezi zimo, ukuthatha amanani aphezulu ama-NSAID bese ulandela ukudla nezinye izinyathelo zokuzivikela kuyoba usizo kakhulu kunokwelashwa kokuvikela isikhathi eside. Kuyinto efiselekayo ukugwema ukudla ngokuqukethwe okuphezulu kwe-purines, ukuphelelwa amandla kwamanzi, ikakhulukazi esimweni sezulu esishisayo, nokusebenza okungavamile okungavamile.
Ama-diuretics kanye ne-acetylsalicylic acid emazingeni aphansi kufanele alawulwe ngokucophelela. Imithi yokuvimbela izidakamizwa kufanele inikezwe kuphela ezigulini ezisengozini enkulu yokuthuthukisa imiphumela yesikhathi eside ye-gout, njenge-arthritis noma isifo esiyingqayizivele sesifo esingenasifo sezinso. Ngokuvamile lezi ziguli ezincane ezinezinga eliphezulu le-uric acid egazini, abantu abane-gout nodular okungavamile noma ukuhlasela okuvame ukuqhuma, nabantu abanezinso zezinso. Esinye sezidakamizwa ezivimbela kakhulu i-allopurinol. Isebenza kahle futhi iphephile ngisho nokusetshenziswa isikhathi eside. Kodwa-ke, ezinye iziguli zikhononda ngokushona, kodwa ngemva kokuyeka umuthi, ilahleka. Isidakamizwa sivimbela i-enzyme xanthine oxidase, eguqula i-xanthine ibe yi-uric acid. Ezinye izidakamizwa ze-prophylactic yi-probenecid ne-sulfin-pyrazone, okwandisa ukwanda kwe-uric acid ngokusebenzisa izinso. I-Gout yisifo esivamile esithinta cishe u-1% wabantu. Kubangela ubuhlungu obuhlangene obubuhlungu. Ngaphambilini, kwahlala "ilungelo" lemibuthano ephakeme yomphakathi, abameleli babo badla ukudla okuningi okucebile emahlathini futhi ukuphila kwabo bekuvame uketshelwa ukuqubuka kwamaphutha kanye nokubhujiswa kwamajoyina. Namuhla, ubuhlungu obunzima obangelwa yisifo singaphathwa ngokuphumelelayo nezidakamizwa eziphikisayo, ngaphezu kwalokho, ukuhlasela okunamandla kungavinjelwa ngezidakamizwa ezinciphisa izinga le-uric acid egazini.