Ku-pathologically, kunezinhlobo ezimbili zalesi sifo: umuntu omdala nomncane. Izinso zePolycystic kungenzeka nge-gossiyo ephethe i-autosomal, okungukuthi, idluliselwa kusuka kumzali kuya komntwana, kahle, noma ifa ngohlobo lwezakhi zofuzo ezizenzekelayo, okungukuthi, lapho abazali bobabili bephethe isifo. Isifo sezinso ze-Polycystic senziwa ngenxa yokuphulwa kwesakhiwo sezinso noma ukwakheka kwayo kanye nokubhuka amabhukhimakhi ngesikhathi sokubeletha, futhi ngezinye izikhathi kuvele inombolo encane yamaseli adingekayo ukuze kusebenze izinso. Ama-cysts akhiwa lapho kukhona ukungabikho okungavamile kokuxhumana phakathi kwe-tubulus ye-renal ngqo ne-glomeruli noma uma bekhubazekile.
Yiziphi izimpawu ezingase ziqiniseke phambi kwesifo futhi kusize ukuqonda: kanjani ukwelapha i-polycystosis yezinso zalokhu noma ukuthi izinga lokunganakwa? Lezi zimpawu ezifana nobuhlungu obunzima nokubuhlungu esifundeni se-lumbar, umfutho wegazi ophezulu, isicanucanu nokuhlanza. Lolu luhlu lwalezo zimpawu ukuthi isiguli ngokwayo siyabona, futhi izibonakaliso ezikhonjiswe kuma laboratories zifaka ukuthi kukhona izibonakaliso zokutheleleka egazini (i-leukocytosis, i-lymphocytosis, i-ESR yanda kancane) ne-hematuria (igazi emcinini) kanye ne-pyuria (i-pus in the urine). Emtholampilo, kafushane, ungasho amagama ambalwa. Incazelo yemibonakaliso yemitholampilo kuleli cala ibaluleke kakhulu, njengoba, njengoba izobhalwa ngezansi, ukwelashwa kwezinso ze-polycystic kuyingozi, okungukuthi, izidakamizwa zikhethiwe ezikhipha izimpawu zesifo. Futhi-ke, izinso ze-polycystic ezinganeni ezincane zimbi kakhulu, ngokuvamile ukubikezela akulungile, umphumela wesifo kuwukufa kwengane kusuka ku-uremia (ukuziqhenya komzimba ngenxa yokungasebenzi komzimba). Kubantu abadala, isifo sezinso ze-polycystic sidlula kancane kakhulu futhi ngokusemthethweni sihlukaniswe ngezigaba ezintathu: isinxephezelo, ukukhokhelwa phansi, ukubuyiswa kwemali. Isigaba ngasinye sinemibono yaso. Esigabeni sokuqala se-polycystic isifo sezinso, okungukuthi, esiteji sesinxephezelo, izibalo azikakabonakali futhi, ngokufanele, akukho izikhalazo ezivela esigulini. Esigabeni sesibili, ukuxhaswa, sekukhona kakade izimpawu zokuhluleka kwenkunzi. Kukhona ukoma okubuhlungu, umlomo owomile, ikhanda eliqinile landa, ukunyuka kwengcindezi yegazi kuyaqina kakhulu. Kukhona i-pyesis yama-cysts, ehambisana ne-chills, i-fever, ekuhlaziyweni kwegazi leukocytosis nokwanda kwe-ESR. Amatshe angase abe ezintsheni angabangela ukuqubuka kwe-renal colic. Futhi uma lesi sifo siya esigabeni sesithathu, i-uraemia iqala. Kulesi sigaba, lesi sifo sincane nakakhulu kunasekubili. Lesi simo sithatha iminyaka, okuholela ekuthuthukiseni ukwehluleka okungapheli komlomo. Ukuwohloka okubuhlungu esimweni sesiguli kwenzeka ngokushesha emva kokunamathiselwe kokutheleleka kwesibili, isibonelo, i-SARS, i-influenza njalonjalo. Ngeshwa, ngemuva kokutholakala kwesifo sezinso ze-polycystic, impilo yeziguli iphakathi kweminyaka engaphezu kwengu-15.
Ngokuphathelene nokuphathwa kwezinso ezithintekayo yi-polycystosis, iphathwa ngokuphawulekayo, okungukuthi, akukho ukwelashwa okuqondile okufanele bonke. Uma isiguli singenzi, futhi kwakungekho ukuhluleka kwezinso ezingapheli, udokotela ubeka ukudla okunomdlandla. Ukucindezelwa kwegazi ukubeka izidakamizwa ezinciphisa ukucindezelwa kwegazi, uma isiguli sinesifo se-pyelonephritis, imithi elwa namagciwane nemithi ye-uroseptic inqunywe. Ukususwa kwe-cysts kanye nokuba khona kwamatshe emathunjini kungadinga ukungenelela okuhlinzayo. Uma kutholakala ama-cyst kuphela angashadile, mane ususe umklamo nge-puncture. Le nqubo yenziwa ngaphansi kwe-anesthesia. Ngemuva kokulahlekelwa ukuzwela, inaliti encane, encane ifakwe ngokubhoboza izinso, kanti umthamo usuke uphelelwa, inaliti efanayo iya kuthathwa ukuhlolwa. Akuzona njalo lezi zindlela zokwelashwa ezisusa zonke izimpawu zesifo nokuphulukiswa kwesiqiniseko, isimo sesiguli, umtholampilo wesifo kuncike kuma-cysts ngokwabo, ubukhulu bawo, umonakalo. Isimo esibucayi kakhulu, uma izinso zilahlekelwa ikhono lokuhlunga umchamo, khona-ke izinso zokufakelwa kanye ne-hemodialysis kuyadingeka, okuyinto esikhathini esizayo ezoholela ekufakweni kwezinso ezinzima. Ngeshwa, ngalesi sifo, ukuzitholela imithi kuyingozi kakhulu isimo sesiguli kanye nenkambo yokugula. Kunoma yiziphi izimo, ukuphulwa kwezinso zezinso kufanele ngokushesha uthintane nodokotela. Njengoba ubuhlungu esifundeni se-lumbar, i-hematuria kanye nokuba khona kokutheleleka kwamagciwane, akufanele uhambe kudokotela kancane kancane. Yebo, njengesilinganiso sokuvimbela, ungathola ukuthi unesihlobo emndenini wakho oye waba nesifo sezinso ze-polycystic. Ngaphambi kwesifo esinjalo, udinga ukuhlolwa okubuhlungu futhi ungabhalisi kancane. Khumbula ukuthi ngesimo sengqondo sokunganakiwe noma sokunganaki, isiguli sinethuba (25%) ukudlulisela lesi sifo kumntwana ozayo.