Lapho ukukhulelwa kushintsha izinga lomathela. Ukwakhiwa kwe-secretion yezingqungquthela ze-salivary kuqukethe ingxube "yokukhumbula" i-calcium ne-phosphate. Njengoba uhlale uhlangana namazinyo, ummatha uhlanza koqweqwe lwawo koqweqwe lwawo, ukuvimbela ukutholakala kwama-caries. Kodwa-ke, ngesikhathi sokukhulelwa, izimfanelo zokuzivikela zokudonsa ngamathambo kakhulu. I-sali ayizigibeli izinsalela zokudla, ayiqedi amabhaktheriya nama-sulfur.
Izinsalela zokudla ezisele ziholela ekwakheni i-plaque ngolimi, amazinyo kanye nezinsini, eziqukethe izifo eziphilayo, futhi ziba ngukugxila kokutheleleka emgodini womlomo.
Ukuthi i-deposit yamazinyo yakhiwa ayimangazi, kuyinqubo yemvelo. Kodwa-ke, ngesikhathi sokukhulelwa, ukukhula okujulile kwama-microorganisms kwenzeka emaqenjini amazinyo kanye nesikhala sokungcebeleka emgqeni wamazinyo, kukhona ingozi yokuthuthukiswa kwezifo zamazinyo. I-plaque ngesikhathi sokukhulelwa ngumthombo wokutheleleka.
Enye ingozi yokwakheka kwamazinyo ukufaka imikhiqizo yomsebenzi obalulekile wama-bacteria okuwumthombo wokutheleleka kwe-fetus.
Uma kungenjalo kususwe ngesikhathi, i-plaque yamazinyo ethambile, kancane kancane igcwele izilonda ezinama-calcareous futhi ixazulula ngokubala kwamazinyo okunzima. Lokho, kuyimbangela yokuvuvukala nokugaya igazi, izifo ze-periodontal kanye ne-caries, kanye nokukhushulwa kwezifo ezikhona.
Ngesikhathi sokukhulelwa, abaningi baphazamiseka yi-calcium metabolism, enomthelela omubi emazinyo, futhi aqala ukwehla ngaphansi kwethonya ngisho nezimbangela ezimbi kakhulu, umthombo owengeziwe wokutheleleka.
Inqubo yokwakheka kwe-plaque ithonywe uhlobo lokudla komama ozayo kanye nokwanela kwemikhiqizo equkethe i-calcium, i-phosphorus, i-vitamin D nezinye izamaminerali namavithamini, izinga le-pH lemali, nokuhlanzeka ngomlomo.
Ngesikhathi esifanele ukuvikela ingane ekungeneni kwe-intrauterine ukutheleleka kanye nesifo se-caries esikhathini esizayo kuyovumela ukuhlanzeka komlomo njalo ngosizo lwezindlela zanamuhla (ama-pastes, amafutha, ama-gels, izintambo, ama-rinses anesifo sengculaza).
Uma uxhumana nodokotela wamazinyo, uhlelo olucacile nolubumbene lwezokwelapha nokuvimbela luyakhiwe. Ukusetshenziswa kwezenzo zokuvimbela ngesikhathi sokukhulelwa kuzokhipha umthombo oyinhloko wokutheleleka, futhi ngabomunye wesifazane ngamunye futhi kunqunywe ngokuhambisana nesimo jikelele, ifomu nokutholakala kwezifo ezihambisanayo.