Ama-protein abhekisela kuma-macromolecules, ahlanganiswa emangqamuzaneni omzimba wethu futhi ayingxenye ebalulekile yamathambo, asebenzayo nezinye izicubu zomzimba. Ukuba khona kwamaprotheni emcimbini womuntu kuyisibonakaliso sokukhubazeka okuqhubekayo emzimbeni wakhe. Kodwa-ke, emcinini wengane, amaprotheni angabakho ngamanani amancane ngokuqhubekayo. Izinkomba ezijwayelekile ziphakathi kwamaprotheni angu-30-60 emaprotheni ekuqoqweni komchamo nsuku zonke, ngokusho kwezinye izindlela zokulinganisa kuze kube ngu-100 milligrams ngosuku.
Amaprotheni amaningi abantu amakhulu kakhulu, ngenxa yokuthi awakwazi ukudlula ohlelweni lokuhlunga izinso. Ngakho-ke, ukubonakala kwamaprotheni emcimbini kubhekwa njengesibonakaliso esingenakuphikwa sokuthi umsebenzi wezinso awunzima, okuwukuthi ukuhlunga kwe-glomerular kuphelelwe amandla.
Ukubonakala kwamaprotheni emcimbini kungaba nemvelo ehlukile, isibonelo, imbangela ingaba khona phambi kwe-agent esebenzayo, ukuthuthukiswa kwezifo zokuhlunga ezincane zezinso noma isitho sonke ngesikhathi esisodwa. Kodwa ngezinye izikhathi ezenzweni zemithi zichazwa lapho amaprotheni emcimbini wezingane engahambisani nezinguquko ekucindezelekeni komzimba, ingane izwa kahle njalo njalo. Lesi simo sivame ukubizwa ngokuthi i-latent orthostatic (cyclic) proteinuria. Ngamanye amazwi, ukubonakala kwamaprotheni emcimbini wengane kuhlotshaniswa nomsebenzi walo emini, isikhundla esiqondile somzimba. Ebusuku, amaprotheni ayanyamalala, ayitholakali ngesikhathi sokulala, lapho ingane isendaweni enezingqimba.
I-proteinuria (ukutholakala kwamaprotheni emcinini) ayihambisani nezimpawu ezibuhlungu. Kodwa-ke, uma inani elikhulu lamaprotheni lingena emcimbini, izinga lalo egazini liyehla kakhulu, okubangela i-edema nomfutho wegazi ophezulu. Ngokuvamile, amaprotheni emcimbini wezingane yisisignali sokuqala saso sonke isifo futhi ikuvumela ukuba ubone ukuthuthukiswa noma ukugeleza kwawo ekuqaleni. Ngakho-ke, kubaluleke kakhulu ukuba izingane ezincane zithathe umchamo ukuze zihlaziywe.
I-Orthostatic Proteinuria
I-Orthostatic proteinuria itholakala ezinganeni zeqembu elidala kanye nabaselula. I-synonym i-proteinuria ehamba phambili, ehambisana nokubonakala kwamaprotheni emcimbini ngesikhathi somntwana. Kuze kube manje, izizathu zokungena kwamaprotheni emcimbini emini azizange zisungulwe ngokungabonakali kokungabikho kwezinkinga zokuhlukumezeka kwenhlanzi nokuhluleka kokuhlunga. Ebusuku, lapho abantwana belele, izinso zabo zihlunga amaprotheni, hhayi ukudlulisela emcinini. Ukuze uhlolisise kahle lesi simo, u-urinalysis wesigaba esinezinyathelo ezimbili, ehlanganisa ukuhlaziya umchamo wokuqala ekuseni oqoqwe ngokushesha ngemva kokulala futhi ingxenye yesibili yomchamo eqoqwe usuku lonke. Lawa masampuli agcinwa kuziqukathi ezahlukene. Uma kwenzeka amaprotheni atholakala engxenyeni yesibili kuphela, ingane ine-orthostatic proteinuria. Engxenyeni yasekuseni yamaprotheni omchamo ngeke atholakale. Kumele kuqashelwe ukuthi i-orthostatic proteinuria yisimo esivamile, esingenabungozi. Ngakho-ke, ungagcini ingane ukuba iqhube ngokomzimba, ayilimazi izinso, nakuba ingabangela ukwanda okwesikhashana ku-protein titer emcinini wengane.
Amaphrotheni emcodini kubantwana: nini ukwelashwa kuyadingeka?
Uma iprotheni ivela emcimbini ngobuncane kanye ne-orthostatic proteinuria, asikho isidingo sokuphatha ingane. Ngokuvamile, udokotela ubeka ukuhlolwa okuphindaphindiwe komchamo ngemuva kwezinyanga ezimbalwa. Lokhu kuyadingeka ukuthola ukuguqulwa kwenani lamaprotheni emcintini.
Lapho kukhona amaprotheni emcimbini ngokuhlolwa okuphindaphindiwe, udokotela angakhipha izivivinyo ezengeziwe ukuze ahlole umsebenzi wezinso ukuze asungule imbangela yeproteinuria. Kungakhathaliseki ukuthi kwenzekani, ukususa amaprotheni kusuka kumchamo akulula kakhulu futhi ezimweni eziningi indlela ephumelelayo kuphela ukuba nokudla okusawoti. Ukudla ukudla ngaphandle kasawoti kusiza ukunciphisa izinga lamaprotheni emcimbini futhi kusiza ukususa ngokushesha futhi kalula. Ezimweni eziyinkimbinkimbi, udokotela ubeka imithi ngemithi. Ngokujwayelekile umthamo wokuqala wezidakamizwa ukhulu, kodwa kancane kancane kunciphisa. Ngezinye izikhathi kufanele uthathe izidakamizwa ezincane zezinyathelo ezinyangeni ezimbalwa. Kubalulekile ukulandela imiyalelo kadokotela.